A model for exercise induced asthma in guinea pigs with lipopolysaccharide and metyrapone 脂多糖和甲双吡丙酮诱发形成豚鼠运动性哮喘(EIA)模型
Objective To investigate the effects of endothelin antagonist, Bosentan on bronchoconstriction elicited by isocapnic hyperpnea in guinea pigs and to explore the effect of endothelin in the pathogenesis of exercise induced asthma ( E1A ). 目的通过内皮素(ET)受体非肽类拮抗剂Bosentan对豚鼠等CO2过度通气模型影响的观察,探讨运动性哮喘(EIA)的发病机制以及ET受体拮抗剂的治疗作用。
Objective In order to study the diagnosis value of bronchial asthma by Exercise Histamine Induced Asthma ( EHIA ). 目的探讨运动-组胺激发试验(EHIA)对支气管哮喘的诊断价值。
Montelukast, as a cysteinyl leukotriene receptor antagonist, is one of the first-line drugs of asthma treatment, is generally considered to have a niche application in the therapy of exercise and aspirin induced asthma. 作为一种半胱氨酰白三烯受体拮抗剂,孟鲁司特是阿司匹林过敏性哮喘和运动性哮喘(EIA)的治疗的一线选择。